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This study investigated the Comprare Esomeprazole On lines of vonoprazan compared with esomeprazole on the healing of post-ESD artificial ulcers. Sixty patients who underwent gastric ESD between May and May were randomized to treatment with vonoprazan V group or esomeprazole E group for 8 weeks. Fifty-three patients were analyzed. The respective 4- and 8-week ulcer healing rates did not differ significantly between V and E groups 8.

Similarly, the respective 4- and 8-week ulcer shrinkage rates did not differ significantly between V and E groups 96. The healing of artificial ulcers after ESD did not differ using vonoprazan or esomeprazole. Both vonoprazan and esomeprazole were effective when used to promote artificial ulcer healing after ESD. As ulcer healing prevents post-ESD bleeding, proton pump inhibitors PPIs are widely prescribed as the first-line Comprare Esomeprazole On line for artificial ulcers developing after ESD. To date, four comparative studies have examined the extent of artificial ulcer healing afforded by P-CAB compared with PPIs.

However, the results were controversial, and further work was required.

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Here, we examined the Comprare Esomeprazole On lines of vonoprazan compared with those of esomeprazole on the healing of post-ESD artificial ulcers in a prospective, multicenter, two-arm, randomized controlled trial RCT and found that the extent of healing of artificial ulcers Comprare Esomeprazole On line ESD was identical when either P-CAB or PPI was prescribed. The study protocol was approved by the ethics review boards of both hospitals, and the trial was registered with the University Hospital Medical Information Network number MIN and performed in accordance with the Declaration of Helsinki.

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