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Pyridone synthetic analogue of nalidixic acid; has a fluorine atom in position 6 increases effect on gram-negative bacteria and piperazine group in position 7 provides activity against Pseudomonas. Norfloxacin is a metabolite of pefloxacin, which differs by the absence of a methyl group at the piperazine nucleus. Norfloxacin is active like in vitro and the results of clinical trials of the oral route for the treatment of a number of infections. Against most strains of the following microorganisms: Active also against Gram-negative microorganisms such as Salmonella spp.

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Reduces the effect of nitrofurans. Overdose Symptoms 3 g per 45 min: There is no specific antidote. Course duration depends on indication for use, the severity of infection and pathogen activity:

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