Does Pravastatin sodium cause hair loss? Pravachol pravastatin is a medication that is used to treat high cholesterol levels. It is in the class of medications called statins, which work by blocking an enzyme in the body that is responsible for the production of cholesterol. Hair loss appears to be a rare side effect associated with this medication, occurring in less than 1 percent of patients taking pravastatin during clinical trials.

Hair loss occurred so infrequently that it is difficult to say whether the medication was responsible for this side effect. For more information on pravastatin, click on this link: Lori Poulin, PharmD Q: What does pravastatin 80 mg look like?

Pravastatin is manufactured by many different companies and therefore can look different depending on the manufacturer. The best way to determine if you have the correct medication would be to contact the pharmacy that you received the medication from. Or you can call your local pharmacy and ask them to identify the pill for you. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.

Megan Uehara, PharmD Q: What dosage does pravastatin come in? Pravachol pravastatin is a medication that is used to treat high cholesterol. It is in the class of medications called statins that work by blocking an enzyme in the liver that produces cholesterol. By blocking this enzyme, it forces the liver to use cholesterol from the bloodstream, and this decreases your cholesterol levels.

This medication comes in 10 mg, 20 mg, and 40 mg tablets. The prescribing information on pravastatin lists the following as common side effects of the medication: Can pravastatin cause a cough?

Pravastatin Pravachol is a statin medication used to treat high cholesterol. Other side effects with pravastatin include cough.

This is not a complete list of the side effects associated with pravastatin. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products.

This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Tell your health care provider about any negative side effects from prescription drugs.

You can also report them to the U. Food and Drug Administration by visiting www. I have been taking pravastatin 40 mg for a couple of years, but I have joint pain everyday. If the symptoms of muscle pain or weakness are accompanied by tiredness, fever, nausea and vomiting, brown or dark-colored urine or yellowing skin, patients should contact their health care provider.

The drug information does not suggest that one statin is more likely to cause muscle pain than another. My husband has been really sick the past 2 months. He's had nausea, diarrhea, muscle weakness, and fatigue. He has taken pravastatin for almost a year.

He takes it at night, wakes up every morning sick to his stomach, cannot eat, and has a loss of appetite. Also had symtoms of a heart attack. He had his heart checked and is okay.

Can pravastatin being causing these symptoms? Pravastatin works in the body by blocking the production of some cholesterol. The medication lowers LDL low density lipoprotein and total cholesterol. The incidence was reported at 7 percent. Diarrhea is a reported side effect in 6 percent of patients. Heartburn has also been reported in 3 percent of patients during clinical trials of the medication.

Fatigue was reported in 4 percent of patients and dizziness has an incidence of reporting at 1 percent to 3 percent. Chest pain is another possible side effect and was reported in 4 percent of patients. Muscle weakness was reported in less than 1 percent of patients. This is not a complete list of all the possible side effects associated with the use of pravastatin.

Myopathy or muscle weakness could be a serious side effect of pravastatin. The fear is that it could be related to rhabdomyolysis, which is the breakdown of muscles. As safety in pregnant women has not been established and there is no apparent benefit to therapy with Pravastatin Sodium during pregnancy, Pravastatin Sodium should be immediately discontinued as soon as pregnancy is recognized [see Contraindications 4.

Limited published data on the use of Pravastatin Sodium in pregnant women are insufficient to determine a drug-associated risk of major congenital malformations or miscarriage. Fetal skeletal abnormalities, offspring mortality, and developmental delays occurred when pregnant rats were administered 10 times to 12 times the MRHD during organogenesis to parturition [see Data].

Advise pregnant women of the potential risk to a fetus. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. Data Human Data Limited published data on Pravastatin have not shown an increased risk of major congenital malformations or miscarriage.

Rare reports of congenital anomalies have been received following intrauterine exposure to other statins. Animal Data Embryofetal and neonatal mortality was observed in rats given Pravastatin during the period of organogenesis or during organogenesis continuing through weaning. Lactation Risk Summary Pravastatin use is contraindicated during breastfeeding [see Contraindications 4. Based on one lactation study in published literature, Pravastatin is present in human milk.

There is no available information on the effects of the drug on the breastfed infant or the effects of the drug on milk production.

Because of the potential for serious adverse reactions in a breastfed infant, advise patients that breastfeeding is not recommended during treatment with Pravastatin Sodium. Advise females of reproductive potential to use effective contraception during treatment with Pravastatin Sodium. Pediatric Use The safety and effectiveness of Pravastatin Sodium in children and adolescents from 8 to 18 years of age have been evaluated in a placebo-controlled study of 2 years duration.

This condition is called hardening of the arteries atherosclerosis. This may lead to: Only a small amount of cholesterol comes from our diet, the majority is made by our own livers.

The body produces most cholesterol at night. A high cholesterol level is generally recognised as adding to the risk of heart disease. The combination of fusidic acid and Pravastatin can lead to serious muscle problems rhabdomyolysis.

If any of the above apply to you, your doctor will need to carry out a blood test before and possibly during your treatment. These blood tests will be used to evaluate your risk of muscle-related side effects. Caution should be exercised when pravastatin is administered to patients with a history of liver disease or heavy alcohol ingestion. As with other HMG-CoA reductase inhibitors statins , pravastatin has been associated with the onset of myalgia, myopathy and very rarely, rhabdomyolysis.

Myopathy must be considered in any patient under statin therapy presenting with unexplained muscle symptoms such as pain or tenderness, muscle weakness, or muscle cramps. In such cases creatine kinase CK levels should be measured see below.

Very rarely in about 1 case over , patient-years , rhabdomyolysis occurs, with or without secondary renal insufficiency. The risk of myopathy with statins appears to be exposure- dependent and therefore may vary with individual drugs due to lipophilicity and pharmacokinetic differences , including their dosage and potential for drug interactions.

CK measurement is indicated before starting statin therapy in these patients see below. The risk and severity of muscular disorders during statin therapy is increased by the co-administration of interacting medicines. The use of fibrates alone is occasionally associated with myopathy. The combined use of a statin and fibrates should generally be avoided. The co-administration of statins and nicotinic acid should be used with caution. An increase in the incidence of myopathy has also been described in patients receiving other statins in combination with inhibitors of cytochrome P metabolism.

This may result from pharmacokinetic interactions that have not been documented for pravastatin see section 4. When associated with statin therapy, muscle symptoms usually resolve following discontinuation of statin therapy. Creatine kinase measurement and interpretation: Routine monitoring of creatine kinase CK or other muscle enzyme levels is not recommended in asymptomatic patients on statin therapy.

However, measurement of CK is recommended before starting statin therapy in patients with special predisposing factors, and in patients developing muscular symptoms during statin therapy, as described below. When measured, CK levels should be interpreted in the context of other potential factors that can cause transient muscle damage, such as strenuous exercise or muscle trauma. Caution should be used in patients with predisposing factors such as renal impairment, hypothyroidism, previous history of muscular toxicity with a statin or fibrate, personal or familial history of hereditary muscular disorders, or alcohol abuse.

In these cases, CK levels should be measured prior to initiation of therapy. CK measurement should also be considered before starting treatment in persons over 70 years of age especially in the presence of other predisposing factors in this population.

The baseline CK levels may also be useful as a reference in the event of a later increase during statin therapy.

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